区别：such是形容词，修饰的是后面的名词或名词词组；而so是副词，只能是用来修饰形容词或副词的。
so还可以表示数量的形容词，与many、few、much、little连用，形成固定搭配。例如She is so diligent a student. 她是个如此勤奋的学生。She is such a diligent student. 她是个如此勤奋的学生。
以下是so和such分别与“that”搭配例句的相关介绍：
He was so ill that two nurses attended on him. 他病得那样重，有两个护士照顾他。He is such a good egg that everyone likes him. 他是一个大好人，个个都喜欢他。
Stress can be the undoing of so many fine players.紧张可能是这许多优秀选手失败的原因。Don't make so much fuss over losing a penny.别为丢了一便士大惊小怪的。
以上资料参考百度百科——such